Dr Michael Tarzi
Consultant Immunologist
MA (Cantab) MD MRCP FRCPath
Specialises in
- Allergic rhinitis and hay fever
- Allergen immunotherapy (desensitisation)
- Food allergy
- Anaphylaxis
- Urticaria and angioedema
I specialise in the diagnosis and management of allergic conditions and related disorders. My clinical expertise includes allergic rhinitis and allergen immunotherapy (desensitisation) for pollen, dust mite and animal dander, as well as insect venom allergy, urticaria and angioedema, anaphylaxis and food allergy. I also have experience in immunodeficiency disorders and can provide general opinion in most clinical settings, although this is no longer my primary focus.
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I have been involved in allergy services and research since 2001, when I joined the allergy department at the National Heart and Lung Institute as a junior doctor and clinical research fellow. I undertook speciality training in clinical immunology from 2003 at The Royal London Hospital and The Royal Free Hospital.
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In 2008, I moved to Brighton to take up a post as senior lecturer and consultant immunologist. Working closely with Professor Frew, I helped to develop the allergy clinic at The Royal Sussex County Hospital. The service was recognised as the regional provider for Sussex in 2012, and I assumed service leadership in 2019.
My clinical workload involves several thousand patient appointments each year, and I have supervised immunotherapy programmes for approximately 600 patients. I hold a number of leadership roles at University Hospitals Sussex NHS Foundation Trust, primarily based at The Royal Sussex County Hospital, including clinical lead for allergy services, diagnostic immunology and blood sciences. I am also a senior lecturer at Brighton & Sussex Medical School, where I lead the year 2 immunology education theme.
Treatment information
Some of the principal treatments carried out by Dr Michael Tarzi at Spire include:
Immunology
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Additional information
Clinical interests
Immunology
Research and publications
Articles
Kudsiova L, Lansley A, Scutt G, Allen M, Bowler L, Williams S, Lippett S, Stafford S, Tarzi M, Cross M, Okorie M. Stability testing of the Pfizer-BioNTech BNT162b2 COVID-19 vaccine: a translational study in UK vaccination centres. BMJ Open Sci. 2021 Sep 12;5(1):e100203.
Gray NJ, Redshaw EL, Isaacs D, Tarzi MD, Smith HE, Frew AJ. Allergy in the elderly: A case note review of referrals to an adult allergy clinic. Clinical & Experimental Allergy. 2018 Sep;48(9):1238-41.
Longhurst H, Cicardi M, Craig T, Bork K, Grattan C, Baker J, Li HH, Reshef A, Bonner J, Bernstein JA, Anderson J. Prevention of hereditary angioedema attacks with a subcutaneous C1 inhibitor. New England Journal of Medicine. 2017 Mar 23;376(12):1131-40.
Longhurst HJ, Tarzi MD, Ashworth F, Bethune C, Cale C, Dempster J, Gompels M, Jolles S, Seneviratne S, Symons C, Price A. C1 inhibitor deficiency: 2014 United Kingdom consensus document. Clinical & Experimental Immunology. 2015 Jun;180(3):475-83.
Beltran L, Koenig M, Egner W, Howard M, Butt A, Austin MR, Patel D, Sanderson RR, Goubet S, Saleh F, Lavender J, Stainer E, Tarzi MD. High-titre circulating tissue transglutaminase-2 antibodies predict small bowel villous atrophy, but decision cut-off limits must be locally validated. Clin Exp Immunol 2014, 176(2):190-198.
Jolles S, Williams P, Carne E, Mian H, Huissoon A, Wong G, Hackett S, Lortan J, Platts V, Longhurst H, Grigoriadou S, Dempster J, Deacock S, Khan S, Darroch J, Simon C, Thomas M, Pavaladurai V, Alachkar H, Herwadkar A, Abinun M, Arkwright P, Tarzi M, Helbert M, Bangs C, Pastacaldi C, Phillips C, Bennett H, El-Shanawany T. A UK national audit of hereditary and acquired angioedema. Clin Exp Immunol 2014; 175: 59-67.
Beltran L, Koenig M, Egner W, Howard M, Butt A, Austin MR, Patel D, Sanderson RR, Goubet S, Saleh F, Lavender J, Stainer E, Tarzi MD. High-titre circulating TTG2 antibodies predict small bowel villous atrophy, but decision cut-off limits must be locally validated. Clin Exp Immunol 2013 (epublished ahead of print)
Smith KA, Gray NJ, Saleh F, Cheek E, Frew AJ, Kern F, Tarzi MD. Characterisation of CD154+ T cells following ex vivo allergen stimulation illustrates distinct T cell responses to seasonal and perennial allergens in allergic and non-allergic individuals. BMC Immunol 2013;14: 49.
Smith KA, Gray NJ, Cheek E, Saleh F, Lavender J, Frew AJ, Kern F, Tarzi MD. Characterisation of CD154+ T cells following ex vivo birch allergen stimulation defines a close relationship between T cell subsets in healthy volunteers. BMC Immunol 2013;14: 14.
Rashid RS, Smith KA, Nambiar KZ, Frew AJ, Tarzi MD. Pollen-food syndrome is related to Bet v 1/PR-10 protein sensitisation, but not all patients have spring rhinitis. Allergy 2011;66: 1391-1392.
Rizzi M, Neumann C, Fielding AK, Marks R, Goldacker S, Thaventhiran J, Tarzi MD, Schlesier M, Salzer U, Eibel H, Warnatz K, Finke J, Grimbacher B, Peter HH. Outcome of allogeneic stem cell transplantation in adults with common variable immunodeficiency. J Allergy Clin Immunol 2011;128: 1371-1374.
Tarzi MD, Grigoriadou S, Carr SB, Kuitert LM, Longhurst HJ. Clinical immunology review series: An approach to the management of pulmonary disease in primary antibody deficiency. Clin Exp Immunol 2009; 155:147-55.
Yong PF, Tarzi M, Chua I, Grimbacher B, Chee R. Common variable immunodeficiency: an update on etiology and management. Immunol Allergy Clin North Am 2008; 28:367-86, ix-x.
Tarzi MD, Hickey A, Forster T, Mohammadi M, Longhurst HJ. An evaluation of tests used for the diagnosis and monitoring of C1 inhibitor deficiency: normal serum C4 does not exclude hereditary angioedema. Clin Exp Immunol 2007; 149:513-6.
Tarzi M, Klunker S, Texier C, Verhoef A, Stapel SO, Akdis CA, et al. Induction of interleukin-10 and suppressor of cytokine signalling-3 gene expression following peptide immunotherapy. Clin Exp Allergy 2006; 36:465-74.
Alexander C, Tarzi M, Larche M, Kay AB. The effect of Fel d 1-derived T-cell peptides on upper and lower airway outcome measurements in cat-allergic subjects. Allergy 2005; 60:1269-74.
Khan S, Tarzi MD, Dore PC, Sewell WA, Longhurst HJ. Secondary systemic lupus erythematosus: an analysis of 4 cases of uncontrolled hereditary angioedema. Clin Immunol 2007; 123:14-7.
Tarzi MD, Jenner M, Hattotuwa K, Faruqi AZ, Diaz GA, Longhurst HJ. Sporadic case of warts, hypogammaglobulinemia, immunodeficiency, and myelokathexis syndrome. J Allergy Clin Immunol 2005; 116:1101-5.
Tarzi MD, Lightman S, Longhurst HJ. An exacerbation of Behcet's syndrome presenting with bilateral papillitis. Rheumatology (Oxford) 2005; 44:953-4.
Tarzi M, Larche M. Peptide immunotherapy for allergic disease. Expert Opin Biol Ther 2003; 3:617-26.
Current NHS posts
Consultant Immunologist, University Hospitals Sussex NHS Foundation Trust.
Contact information
| Telephone | Insured 01273 828 030 || Self-pay 01273 828 148 |
| Private secretary | Anne Hillman |
| Private secretary telephone | 07474 363 704 |