Dr Wycliffe Mbagaya

Dr Wycliffe Mbagaya

Consultant in Metabolic Medicine


"Spire Bristol Hospital is easy to access and offers a supportive environment for patients and staff."

Specialises in

  • Metabolic medicine and syndrome
  • Vitamin and mineral deficiency
  • Cholesterol disorders
  • Fatigue and unexplained symptoms
  • Abnormal blood tests

I am a Consultant in Metabolic Medicine and Clinical Biochemistry at University Hospitals Bristol and Weston NHS Trust. I run busy diabetes, lipid and inherited adult metabolic clinics, with continued leadership in laboratory medicine.

I have extensive experience in metabolic medicine, specialising in the treatment and management of diabetes, lipid disorders, electrolyte imbalance and inherited metabolic diseases. I manage patients with various metabolic conditions, including unexplained fatigue, trimethy laminuria and other malodour syndromes and regularly advise patients and other doctors on blood test results and their implications.

I am particularly interested in the management of mineral and nutrient deficiencies, such as hypomagnesaemia, phosphate deficiency and vitamin D deficiency. With my background in metabolic medicine, I have an insight in the management of metabolic effects of medications such as antidepressants, antipsychotics, chemotherapy and immune modulators. I see patients for metabolic optimisation before surgery, pregnancy and the recovery phase.

In addition to my clinical roles, I participate in clinical research. I’ve been a principal investigator and sub-investigator in a number of novel cholesterol medications, with some now in practice and was an early prescriber of injectable cholesterol medications and GLP-1 agonists.

I am a Clinical Director for Laboratory Medicine at University Hospitals Bristol and Weston NHS Trust. Alongside my clinical work, I’m an Honorary Senior Lecturer at the University of Bristol, teaching both students and doctors in training. I regularly teach on nationwide GP courses on metabolic disorders and laboratory medicine.


General Medical Council Number: C6084896

Treatment information

Some of the principal treatments carried out by Dr Wycliffe Mbagaya at Spire include:

Metabolic medicine

Other treatments

  • Electrolyte imbalance
  • Fish odour syndrome
  • Hypercholesterolaemia
  • High cholesterol
  • Metabolic diseases
  • Metabolic effects of medication
  • Metabolic optimisation
  • Metabolic syndrome
  • Personalised medicine
  • Prediabetes
  • Vitamin and mineral deficiency

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Additional information

Clinical biochemistry
Diabetic medicine
General medicine
Stroke prevention
Thyroid disease

MB ChB / Moi Universty Kenya / 1999
Bachelor of Medicine, Bachelor of Surgery
MB ChB is a degree given to physicians at the basis of their training

Professional memberships

Association of Clinical Biochemistry

British Inherited Metabolic Diseases Group

European Atherosclerosis Society

Fellowship of Royal College of Physicians of Edinburgh

Fellowship of Royal College of Pathologists

Professional leadership

I am the Clinical Lead for Pathology at Weston General Hospital and Year 3 Lead for University of Bristol North Somerset Academy.


Mbagaya W, Luvai A, Waise A. Diagnostic biochemical markers for heart failure. Pract Diab 2018: 35; 149-151

Barth JH, Luvai A., Jassam N, Mbagaya W, Kilpatrick ES, Narayanan D, Spoors S. Comparison of method-related reference intervals for thyroid hormones: studies from a prospective reference population and a literature review. Ann Clin Biochem 2017: 55;107-112

Mbagaya W, Luvai A, Lopez B. Biological variation of troponin in stable haemodialysis Patients. Ann Clin Biochem 2015: 52;562-568 Luvai

Consultant in Metabolic Medicine, University Hospitals Bristol and Weston NHS Trust.

Honorary Senior Clinical Lecturer, University of Bristol.

I enjoy spending time with my wife and two daughters, cycling and walking in the countryside.

Private secretary Hayley Thomas
Private secretary telephone 0754 822 2332
Private secretary email Hayley@remotepa.uk