Professor  Parwez Hossain

Professor Parwez Hossain

Associate Professor in Ophthalmology and Consultant Ophthalmic Surgeon
MB, ChB, PhD, FRCOphth, FRCS (ED)

Practising at

Spire Southampton Hospital

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Treatment information

Some of the principal treatments carried out by Professor Parwez Hossain at Spire include:

Ophthalmology at Spire Southampton Hospital

Other treatments

  • Keratoplasty
  • Corenal Transplant Surgey 
  • Pterygium Surgery
  • Dry Eye Treatment
  • Corneal Infections Treatment
  • Keratoconus and Collagen Cross Linking
  • Herpetic Keratitis & Corneal Anti-Angiogenic Therapy

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Professional profile

I am a Associate Professor in Ophthalmology at the University of Southampton & Consultant Ophthalmologist at Eye Unit, University Hospitals NHS Foundation Trust. I am an Associate Editor for ‘Eye’, the scientific journal for the Royal College Ophthalmologists and an NHS Bronze Clinical Excellence Award holder.

I qualified in Medicine from Aberdeen University and trained in Ophthalmology in Aberdeen, Nottingham, Leicester and Bascom Palmer Eye Institute, Miami, USA. I sub-specialise in Cornea & External Eye Disease, run a busy tertiary referral center for the Southampton Eye Unit, Southampton University Hospital NHS Trust and take care of a diverse range of corneal diseases. Clinical Expertise – Cornea, Cataract & External Eye Disease.

My main interest is in treating all types of Cornea & External Disease, these conditions include a range of conditions such as Cataracts, Blepharitis, Dry Eye Disease, Fuchs Endothelial Dystrophy, Keratoconus, Herpetic Eye Disease, Meibomian Gland Dysfunction and Pterygium Treatment may include tailored medical therapy (novel eye drops, specific non-drug therapy) or involve surgery in the form of corneal transplantation (e.g. endothelial keratoplasty/pterygium surgery) - with over 1,000 procedures performed - or other forms of anterior segment/ocular surface eye surgery (e.g. collagen cross-linking for keratoconus). I also perform routine and complex cataract surgery, often in patients with a high risk profile (I have performed over 3,000 procedures). I have extensive experience on use of intraocular lenses to obtain the optimal refractive outcomes for my cataract surgery e.g. would a Toric Intraocular Lens be more suitable over a standard lens? Is it better to use multifocal/extended depth of lens? Each of my patients has a detailed refractive, occupational and, where necessary, corneal topographic assessment so that this can be evaluated. Post-cataract surgery, my patients are predominantly made spectacle independent but each patient has different requirements and the surgical plan is tailor-made for the individual.

My patient referral base is very large with patients coming from all over the UK, Eire and the Channel Islands. For further information on my NHS clinical practice please see: http://www.uhs.nhs.uk/ContactUs/Directoryofconsultants/Consultants-by-service/Eyes-ophthalmology-consultants/Corneal-and-external-eye-disorders/HossainMrParwez.aspx

In my university/academic role, I run an active research programme (see below) to determine the optimal treatments in patients with cornea & external eye disease. As a result, both my NHS and private patients benefit from up to date advice on the latest therapies available for their conditions. Research Background – Developing New Therapies /Surgery for Cornea & Cataract Disease. My clinician-scientist career started at Aberdeen University where I was awarded a Welcome Trust Fellowship to study the mechanisms of lymphocyte traffic in ocular inflammation. In my PhD thesis, I established a novel method for in vivo tracking of immune cells in the posterior segment of the eye. The technique allowed the interactions of lymphocytes with an inflamed vascular endothelium to be observed and quantified.

Following my PhD, I was appointed Clinical Lecturer at Nottingham University, there my interest focused on investigating the innate immune mechanisms during corneal inflammation. I found that the immune adhesion molecule CD34 is a unique marker for human corneal stromal keratocyte (corneal fibroblast) activation. While at Nottingham, I also helped to establish the effectiveness of a new surgical technique called ‘Fine Needle Diathermy’ to treat long standing corneal vascularization. This treatment helps against chronic corneal vascularization such as from herpes keratitis or chronic corneal graft rejection and has been adopted around the world. I also developed techniques in corneal confocal imaging and my work has highlighted the benefit of this in the early detection of diabetic peripheral neuropathy (published in The Lancet).

At Southampton I lead a corneal infection research group comprising a post-doctoral fellow, PhD & undergraduate research students. My research focus is to develop new diagnostic techniques for corneal infections such as anterior segment OCT and novel microbial diagnostic detection platforms. I also run a clinical surgical research programme with the aim to develop optimal methods for keratoplasty, including laser based approaches. As part of the UK Collagen Cross-linking Consortium, me and my team at Southampton have performed over 300, using an accelerated protocol collagen cross-linking procedures for keratoconus patients with favorable outcomes. For further research information please see weblink http://www.southampton.ac.uk/medicine/about/staff/parwez.page

Clinical Interests


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Current NHS posts

Associate Professor in Ophthalmology, University of Southampton.

Consultant Ophthalmic Surgeon, Cataract, Cornea and External Eye Disease, University Hospitals Southampton NHS Trust.

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Financial Interests

Holds less than 0.1% of shares in Spire Healthcare Group Plc

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Private contact details

Website http://www.som.soton.ac.uk/staff/profile.asp?parwez
Private secretary Peter Ryan
Private secretary telephone 023 8076 4309
Private secretary fax 023 8076 4994
Private secretary email peter.ryan@spirehealthcare.com

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