GeneHealth UK

27 February 2015

Carriers of BRCA 1 & 2 genes have up to 85% lifetime risk of breast cancer. The BRCA 1 & 2 genes can be identified with a blood test that looks at the client’s DNA.

As BRCA 1 & 2 carriers have a significantly increased risk of breast cancer, some women may decide to have a risk reducing double mastectomy. This can reduce the risk of breast cancer to approximately 5% over a lifetime. It can take 4-6 weeks to get the gene test result. 

In addition to the comprehensive BRCA 1 & 2 gene test, Spire Cardiff Hospital will also provide a special test for Ashkenazi Jewish individuals who have a higher risk of having a BRCA mutation (2.5% compared to 0.2% in the non-Jewish population). This test will look for three common mutations, which are found in specific locations in the BRCA genes. This is a faster test to run, with results normally available within two weeks. 

Carriers of BRCA 1 & 2 mutations have a significantly increased risk of breast cancer and therefore frequently make screening and treatment decisions on the basis of their genetic test results. For this reason, Spire Cardiff has included in the price of the gene tests a pre and post-test consultation with a genetic counsellor.

During these consultations a leading genetic counsellor will fully explain the pros and cons of BRCA testing, personal risk and what options are available, depending on the test result. After the test there is another consultation, which will explain the test results and support the patient in making an informed decision.

GeneHealth UK also offers BowelGene, BreastGene and ProstateGene, which are cancer panel tests. These tests sit on the NGS platform and analyse multiple genes simultaneously, full details are available at their website

In light of the NICE guidelines GeneHealth UK also offers a chemoprevention service. For those clients at moderate or high risk of breast cancer, an experienced genetic counsellor will provide a detailed risk assessment and one-hour consultation explaining the risks and benefits of chemoprevention. 

Pre-conception testing, looking for over 200 diseases is also available from Spire Cardiff.

Spire Cardiff Hospital has teamed up with GeneHealth UK’s genetic counsellor Caroline Kirwan. Caroline is a UK registered genetic counsellor, with 15 years' experience covering all aspects of genetic counselling, and is currently working as a senior genetic counsellor with the All Wales Medical Genetics Service. Caroline arrived in Cardiff eight years ago having worked at St Mark’s Hospital, London and Addenbrookes Hospital, Cambridge.

Mrs Caroline Kirwan, genetic counsellor, GeneHealth UK said: “The opening of the Genetic Counselling and Testing Clinic at Spire Cardiff is a really positive move at exactly the right time. The understanding of genetic testing is increasing rapidly amongst scientists, clinicians and the population in general but very few clinics offer both the face-to-face counselling and state-of-the-art gene testing. Excitingly next generation sequencing now offers us the opportunity to analyse multiple genes at once and promises to be the future of genetics.”  


  • BRCA 1 & 2: £1,300 including two hours of counselling, reporting time 4-6 weeks
  • Ashkenazi Jewish Mutation test: £820 including two hours of counselling, reporting time 2-3 weeks
  • Single site mutation test (predictive testing): £720, including two hours of counselling reporting time 2-3 weeks
  • BowelGene, BreastGene, OvarianGene and ProstateGene: £1,500 including two hours of counselling, reporting time 10 weeks
  • Pre-conception: £850 including counselling, reporting time 4-5 weeks
  • Genetic counselling: £150 per hour

About GeneHealth UK

GeneHealth UK is the leading UK provide of private genetic testing and offers face-to-face consultation at a growing number of clinics and over the phone. All genetic tests are offered by genetic counsellors with pre and post test counselling using state-of-the-art testing facilities.

Services are available as self-pay and, for selected indications, some insurance companies will cover the testing. 

GeneHealth UK is part of International HealthScreen Technologies Ltd. offering the largest range of early detection of cancer services in the UK and overseas. - 0800 331 7177

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