Dr Sethupathi Muthuramalingam

Dr Sethupathi Muthuramalingam

Consultant Oncologist


Specialises in

I graduated from India and obtained an MD in General Medicine from one of the prestigious central institutes (JIPMER) in India. I was awarded a Gold medal by the University for the most outstanding performance in the MD examination.

My general oncology training started in the Republic of Ireland and then I spent fours years in the Oxford Medical Oncology training programme, leading to the completion of specialist training in oncology. I took part in various research activities during my training and I was awarded the American Society of Oncology Merit Award for the quality research paper abstract submitted in one of their meetings.

In 2005 I was appointed as a Consultant Medical Oncologist at Portsmouth Hospitals NHS Trust. As an oncologist with a special interest in colorectal, lung cancer and mesothelioma, my expertise is treating cancer patients with chemotherapy, biological therapies, targeted therapies and also immunotherapies.

I also use molecular tests like next generation sequencing (NGS) and genetic tests to guide treatment decisions and reduce the toxicities from treatment. In addition, I take part in many clinical trials and I was the principal investigator of a few of the trials. I have extensive knowledge in managing symptoms associated with cancer and I work very closely with the palliative care and pain team.


Treatment information

Some of the principal treatments carried out by Dr Sethupathi Muthuramalingam at Spire include:


Other treatments

  • Biological therapies
  • Immunotherapies
  • Targeted therapies

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Important information about Covid-19 tests

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Additional information

Special clinical interests: Chemotherapy for colorectal, lung cancer and mesothelioma. Use of the biological therapies in the treatment of cancer like bevacizumab, cetuximab, Panitumumab. Use of the targeted therapies in the treatment of cancer like gefitinib, afatinib,criziotinib. Use of the immunotherapies in the treatment of cancer like Pembrolizumab, nivoulumab. Application of Molecular tests including next generation sequencing (NGS) which help to guide targeted treatments. Application of Genetic tests like DPD and MSI, which might influence treatment decision making in colorectal cancer patients.

Professional memberships

Royal College of Physicians

Association of Cancer Physicians

American Society of Clinical Oncology

British Medical Association

European Society of Medical Oncology

Medical Defence Union

International Association of Lung Cancer

Health Volunteers Overseas

Professional leadership

Lead for the chemotherapy services: 2009-2016 Portsmouth Hospitals NHS trust
Lead for the chemotherapy Governance and peer reviews: 2009-2016
Represented Portsmouth in the network chemotherapy network meetings: 2009-2016
Represented chemotherapy services in the Formulary Medicines Group meetings: 2011-2016 Portsmouth Hospitals NHS trust
Chair of the oncology Consultant group meetings: 2013-2014
Portsmouth Representative: 2011-2013 Regional ‘Cancer Drugs and Therapeutics Evaluation committee’ (CDTEC) meeting

I actively take part in many Phase III trials for colorectal and lung cancers. I am also the local Principal Investigator for some of the Phase III trials.

Media Coverage

Learn the signs of lung cancer

Consultant Medical Oncologist, Portsmouth Haematology Oncology Centre, Queen Alexandra Hospital, Portsmouth.

I enjoy music and travelling in my free time.

Private secretary Deborah Otter
Private secretary telephone 07490 415 990
Private secretary email secretary@drramprivatepractice.co.uk