Dr Stephen Middleton

Consultant Gastroenterologist


"Spire Cambridge Lea hospital provides an excellent platform where I can provide the highest quality of care. The staff are highly efficient while also maintaining a very pleasant and kind attitude at work."

Specialises in

Also available for:

Virtual consultations:

My specialist areas of particular interest include irritable bowl syndrome (IBS), constipation, colitis, crohn's, indigestion and swallowing disorders. I have over 20 years experience in conducting therapeutic colonoscopy, endoscopy and inpatient gastroenterology. I have extensive clinical experience in general medicine as well as gastroenterology and continue an active research programme which is important to stay at the leading edge of developments.

During the last 25 years, I have performed over 10,000 colonoscopies, over 20,000 gastroscopies, have undertaken between 4 and 5 gastroenterology outpatient clinics per week and have nearly 20 years experience with oesophageal physiology studies.

I was a Consultant Gastroenterologist at Addenbrooke’s, University of Cambridge Teaching Hospital (now retired). I was appointed to this position in 1995 and was the senior gastroenterologist in a unit of eight consultants. Over this period in Cambridge I established and developed an irritable bowl syndrome (IBS) service, upper GI cancer service, therapeutic gastroscopy service, oesophageal physiology service, and been the medical advisor for the local Crohn's and Colitis Association. I have also been the lead physician for the intestinal transplant service for 20 years, which has kept me up to date with the most difficult gastroenterological conditions.

I am the clinical lead of the gastroenterology physiology unit which I founded in 1997 and now provide a regional service for oesophageal manometry and ambulatory pH studies to investigate swallowing problems and indigestion.

I am the clinical lead of the Cambridge service for irritable bowel syndrome. The service uses dietary treatment as the primary mode of treatment. An audit of a 1,000 patients and the dietary treatment was found to be successful in over 70%. I have recently described a new syndrome of rapid gastric emptying and reactive hypoglycaemia (low blood sugars) and have introduced a new test (The SMART PILL) which is swallowed and wirelessly transmits pressure, temperature and pH from the entire GI tract representing a quantum leap forward in technology. I am currently working on a new test to identify food intolerance in irritable bowl syndrome (IBS) and the importance of micro flora of the colon. This could lead to new pro-bitoic and pre-biotic therapies.

I am also an associate clinical lecturer and senior research fellow at Cambridge University and Honorary Professor of Gastroenterology at Plymouth University Peninsular School of Medicine.


Treatment information

Some of the principal treatments carried out by Dr Stephen Middleton at Spire include:


Other treatments

  • Ano-rectal biofeedback (bowel retraining) and physiology
  • Wireless capsule motility study (SMART Pill)
  • Wireless oesophageal pH study (BRAVO study) glucose and lactose hydrogen breath test

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Important information about COVID-19 tests

COVID-19 testing or antibody tests are not available as a standalone service at Spire Cambridge Lea Hospital.


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Additional information

Bowel disease
Gastrointestinal cancer
Inflammatory bowel disease
Motility disorder

Professional memberships

British Medical Association (BMA)

Royal College of Physicians

British Society of Gastroenterology

Small intestinal Transplantation Association

British Association for Parenteral and Enteral Nutrition

Professional leadership

Lead clinician for IBS at Addenbrooke's Cambridge University teaching Hospital
Lead physician for intestinal transplantation at Addenbrooke's Cambridge University teaching Hospital
Lead clinician for gastrointestinal motility at Addenbrooke's Cambridge University teaching Hospital
Co-chair of national adult intestinal transplantation forum

Out of work, for physical exercise I enjoy hill walking in the UK and abroad, skiing, sailing and swimming. I also enjoy chess, history, navigation, music and theatre.

Telephone 01223 266 990
Email sjmiddleton7@outlook.com
Website http://www.sjmiddletongastro.net/
Private secretary Mrs Helen Middleton
Private secretary telephone 01767 677 810
Private secretary fax 01767 677 810
Private secretary email sjmiddleton7@outlook.com