Mr Parwez Hossain

Mr Parwez Hossain

Associate Professor in Ophthalmology and Consultant Ophthalmic Surgeon
MB, ChB, PhD, FRCOphth, FRCS (ED)

Practising at

Spire Southampton Hospital

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Treatment information

Some of the principal treatments carried out by Mr Parwez Hossain at Spire include:


Other treatments

  • Keratoplasty
  • Corenal Transplant Surgey 
  • Pterygium Surgery
  • Dry Eye Treatment
  • Corneal Infections Treatment
  • Keratoconus and Collagen Cross Linking
  • Herpetic Keratitis & Corneal Anti-Angiogenic Therapy

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Professional profile

Parwez Hossain is Associate Professor in Ophthalmology at the University of Southampton & Consultant Ophthalmologist at Eye Unit, University Hospitals NHS Foundation Trust. He is an Associate Editor for ‘Eye’, the scientific journal for the Royal College Ophthalmologists and NHS Bronze Clinical Excellence Award holder.

Parwez qualified in Medicine from Aberdeen University and trained in Ophthalmology in Aberdeen, Nottingham, Leicester & Bascom Palmer Eye Institute, Miami, USA. He sub-specialises in Cornea & External Eye Disease, runs a busy tertiary referral center for the Southampton Eye Unit, Southampton University Hospital NHS Trust, takes care of a diverse range of corneal diseases. Clinical Expertise – Cornea, Cataract & External Eye Disease

Parwez’s main interest is in treating all types of Cornea & External Disease, these conditions include a range of conditions such as Cataracts, Blepharitis, Dry Eye Disease, Fuchs Endothelial Dystrophy, Keratoconus, Herpetic Eye Disease, Meibomian Gland Dysfunction, Pterygium Treatment may include tailored medical therapy (novel eye drops, specific non-drug therapy) or involve surgery in the form of corneal transplantation (eg endothelial keratoplasty / pterygium surgery) (over 1,000 procedures performed) or other forms of anterior segment / ocular surface eye surgery (eg collagen cross-linking for keratoconus). Parwez also performs routine and complex cataract surgery, often in patients with a high risk profile (performed over 3,000 procedures). He has extensive experience on use of intraocular lenses to obtain the optimal refractive outcomes for his cataract surgery eg would a Toric Intraocular Lens more suitable over a standard lens? Is it better to use multifocal /extended depth of lens? Each of Parwez’s patients has a detailed refractive, occupational and, where necessary, corneal topographic assessment so that this can be evaluated. Post-cataract surgery, Parwez’s patients are predominantly made spectacle independent but each patient has different requirements and the surgical plan is tailored made for the individual.

Parwez’s patient referral base is very large with patients coming from all over the UK, Eire & the Channel Islands. For further information on his NHS clinical practice please see

In his university/academic role, Parwez runs an active research programme (see below) to determine the optimal treatments in patients with cornea & external eye disease. As a result, both Parwez’s NHS & private patient benefit from up to date advice on the latest therapies available for their conditions. Research Background – Developing New Therapies /Surgery for Cornea & Cataract Disease Parwez's clinician-scientist career started at Aberdeen University where he was awarded a Wellcome Trust Fellowship to study the mechanisms of lymphocyte traffic in ocular inflammation. In his PhD thesis, he established a novel method for in vivo tracking of immune cells in the posterior segment of the eye. The technique allowed the interactions of lymphocytes with an inflamed vascular endothelium to be observed and quantified.

Following his PhD, Parwez was appointed Clinical Lecturer at Nottingham University; there his interest focused on investigating the innate immune mechanisms during corneal inflammation. He found that the immune adhesion molecule CD34 is a unique marker for human corneal stromal keratocyte (corneal fibroblast) activation. Whilst at Nottingham, he also helped to establish the effectiveness of a new surgical technique called ‘Fine Needle Diathermy’ to treat long standing corneal vascularization. This treatment helps against chronic corneal vascularization such as from herpes keratitis or chronic corneal graft rejection and has been adopted around the world. Parwez also developed techniques in corneal confocal imaging and his work has highlighted the benefit of this in the early detection of diabetic peripheral neuropathy (published in The Lancet).

At Southampton, he leads a corneal infection research group comprising a post-doctoral fellow, PhD & undergraduate research students. His research focus is to develop new diagnostic techniques for corneal infections such as anterior segment OCT & novel microbial diagnostic detection platforms. He also runs a clinical surgical research programme with the aim to develop optimal methods for keratoplasty, including laser based approaches. As part of the UK Collagen Cross-linking Consortium, he and his team at Southampton have performed over 300, using an accelerated protocol collagen cross-linking procedures for keratoconus patients with favorable outcomes. For further research information please see weblink

Clinical Interests

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Current NHS posts

Associate Professor in Ophthalmology, University of Southampton

Consultant Ophthalmic Surgeon, Cataract, Cornea and External Eye Disease, University Hospitals Southampton NHS Trust

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Financial Interests

Holds less than 0.1% of shares in Spire Healthcare Group Plc

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Private contact details

Private secretary Peter Ryan
Private secretary telephone 023 8076 4994
Private secretary fax 023 8076 4309
Private secretary email