Dr Ari Manuel

Respiratory, Sleep and Ventilation Consultant

Dr MBBS (Imperial) BSc (Imperial) MRCP (UK) DPhil (Oxford)


Specialises in

  • Respiratory medicine
  • Sleep disorders

I am passionate about improving care for those patients diagnosed with sleep disordered breathing (SDB) in the UK. My aim is that all patients with SDB are identified in a timely manner, undergo the correct tests and subsequently receive the correct treatment. Once on treatment, they should be able to access services that support them and their families and be regularly reviewed to ensure they remain on the correct therapy. This needs to be underpinned by robust and clear parameters for healthcare practitioners to follow: all of these processes need be based on the highest possible level of evidence with well-constructed guidelines.

During my clinical and academic career my guiding aim has always been to improve the patient pathway for those who suffer with sleep disordered breathing. I have worked in sleep units for over 10 years in both a clinical and an academic capacity, with the last three years as a Consultant. My career thus far has seen me working in both urban and rural settings, treating a large cross-section of society. I have continued to hone my practice within large tertiary centres and small falling district general hospital units alike, greatly expanding my skillset and knowledge base.

During my academic tenure at Oxford during my PHD, a key aspect to my work was the ability to gather data, analyse and critique it to a high standard, in order to synthesise useful conclusions. This led to a peer reviewed publication and an editorial on the work I had done in a well-known Respiratory journal. I have had the opportunity to apply these skills in other forums, such as contributing to the BTS Driving guidelines for patients with OSA (which I am currently involved in).

I work on a number of national committees (BTS, Royal Society of Medicine and British Sleep Society) which make me acutely aware of the current challenges to provision of services for patients suffering with SDB. Having worked on a number of guidelines for the BTS, in important areas such as Oxygen prescription and Smoking cessation I am well familiarised to the social, political and economic influences on organisation such as NICE. During my time involved in BTS Special Advisory groups, I have had the satisfaction not only of implementing guidelines that I have helped to create in a clinical setting, but in knowing that other professionals have been able to support patients to achieve the best pathway of care for their needs.

I have worked with the All Party Government Group for Obesity and the fellow to the CEO of the NHS England: I am well versed in the challenges that face us as practitioners in the NHS, as well the issues of inequality in health, public health and social care in regards to access to SDB services for patients.

Three years in a row I have appeared on national radio, broadcasting a show to promote healthy lifestyle and weight management to a target audience of socially disadvantaged ethnic minorities. Public and relevant stakeholder engagement is key to the success of a national guideline and am well situated to facilitate this. I am also a medical trustee to the Hope-2-Sleep Sleep apnoea charity and am also working with the British Lung Foundation on updating their information on sleep apnoea.

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General Medical Council Number: C6076363

Treatment information

Some of the principal treatments carried out by Dr Ari Manuel at Spire include:

Respiratory medicine

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Important information about Covid-19 tests

Spire Murrayfield Hospital Wirral is only able to provide Covid-19 tests to patients undergoing surgery at our hospital. Covid-19 testing or antibody tests are not available as a standalone service.

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Additional information

Clinical interests

Sleep disorders
Respiratory medicine

Qualification and professional memberships

Clinical Medicine / University of Oxford / 2015
DPhil

Ultrasound / Royal College of Radiology / 2014
Level 1

Respiratory Medicine / Royal College Physicians of the United Kingdom / 2014
MRCP

Diploma in Learning and Higher Education / University of Oxford / 2013
Diploma

Postgraduate Education / Royal College of Physicians of the United Kingdom / 2008
MRCP

Bachelor of Medicine, Bachelor of Surgery / Imperial College School of Medicine, London / 2003
MBBS (with Honours)

Biochemistry / Imperial College School of Medicine, London / 2000
BSc

MBBS / Imperial / 2003
Bachelor of Medicine and Surgery


Professional memberships

2017 - Present Council Member for Sleep Medicine, Royal Society of Medicine

2017 - Present Member of British Thoracic Society, Sleep Society

2013 - 2016 Member of the British Thoracic Society council

Research and publications

  • Is a raised bicarbonate, without hypercapnia, part of the physiologic spectrum of obesity-related hypoventilation? ARG Manuel, N Hart, JR Stradling CHEST 2015 Journal 147 (2), 362-368
  • Exploratory study into the effect of abdominal mass loading on airways resistance and ventilatory failure BMJ Open Respiratory Research 2016 3 (1), e000138 RS Dattani, CB Swerner, JR Stradling, ARG Manuel
  • Correlates of obesity-related chronic ventilatory failure BMJ open respiratory research 2016 3 (1), e000110 AR Manuel, N Hart, JR Stradling
  • Biomarkers of oxidative stress following continuous positive airway pressure withdrawal: data from two randomised trials European Respiratory Journal, ERJ-00232-2015 JR Stradling, EI Schwarz, C Schlatzer, AR Manuel, R Lee, C Antoniades
  • Markers of adipose tissue hypoxia are elevated in subcutaneous adipose tissue of morbidly obese patients with hypoventilation syndrome and obstructive sleep apnoea syndrome but not in the moderately obese. Society for Endocrinology BES 2015 M Todorčević, L Austen, A Manuel, Z Michailidou, J Stradling, F Karpe
  • Quality of life, diet and exercise measurements in obese individuals with and without ventilatory failure. Obesity research & clinical practice 9 (6), 639 2016 C Turnbull, A Manuel, J Stradling

Contact information

Telephone 0151 648 7000