Dr Jonathan Nolan

Dr Jonathan Nolan

Consultant Gastroenterologist

Practising at

Spire Gatwick Park Hospital

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Treatment information

Some of the principal treatments carried out by Dr Jonathan Nolan at Spire include:


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Professional profile

Dr Nolan has been working as a consultant gastroenterologist at East Surrey Hospital for two years and is an expert in nutrition, malabsorption and bile acid diarrhoea.

Dr Nolan specialises in most aspects of luminal gastroenterology including irritable bowel syndrome, nutrition, inflammatory bowel disease and functional GI disturbances. He has been training to become a gastroenterologist since 2005 in hospitals across North West London including St Mark's Hospital Intestinal Failure Unit from 2008 and 2009 giving detailed experience in clinical nutrition. Dr Nolan took time out from training to undertake research leading to the award of a PhD at Imperial College London at Hammersmith, St Mary's and Charing Cross Hospitals from 2010-2014. The research was centered on the physiology and new treatments for symptoms of bile acid diarrhoea in irritable bowel syndrome and Crohn's disease.

Dr Nolan has now performed close to 1,000 colonoscopies and over 2,000 gastroscopies and is proficient in all aspects of endoscopy including polyp removal and surveillance and chromoendoscopy assisted colonoscopic surveillance of inflammatory bowel disease.

Dr Nolan is currently the lead clinician for Nutrition at East Surrey Hospital and chair the Nutrition Steering Group Committee.

Dr Nolan currently maintain an honorary contract at Imperial College London.

Clinical Interests

Inflammatory bowel disease
Motility disorder

Irritable bowel syndrome

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Qualification and professional memberships

MBBS / Imperial College School of Medicine, St Mary's Hospital / 2002
Bachelor of Medicine, Bachelor of Surgery

BSc / University College London / 1999
Bachelor of Science: Neuroscience - Upper Second Degree

MCRP / Royal College of Physicians, London / 2006
Member of the Royal College of Physicians

PhD / Imperial College London / 2016
Doctor of Philosophy
Research Degree awarded for research into bile acid diarrhoea

Professional memberships

Member of the Royal College of Physicians
Member of the British Society of Gastroenterologists
Member of the British Association of Parenteral and Enteral Nutrition

Professional leadership

Lead Clinician for Nutrition at Surrey and Sussex Healthcare NHS Trust

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Current NHS posts

Consultant Gastroenterologist and Lead Clinician for Nutrition at Surrey and Sussex Healthcare NHS Trust

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Research and Publication


Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants. Lee JM, Ong JR, Vergnes L, de Aguiar Vallim TQ, Nolan J, Cantor RM, Walters JRF, Reue K.J Lipid Res. 2018 Jan 2

Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea. Johnston IM, Nolan JD, Pattni SS, Appleby RN, Zhang JH, Kennie SL, Madhan GK, Jameie-Oskooei S, Pathmasrirengam S, Lin J, Hong A, Dixon PH, Williamson C, Walters JR. Am J Gastroenterol. 2016 Mar;111(3):423-32

Walters JRF, Johnston IM, Nolan JD, Vassie C, Pruzanski ME, Shapiro DA. The response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid. Aliment Pharmacol Ther 2015; 41: 54-64

Nolan JD, Johnston IM, Pattni SS, Dew T, Orchard T, Walters JR. Diarrhea in Crohn's Disease: investigating the role of the ileal hormone Fibroblast Growth Factor 19. J Crohns Colitis. 2014 Dec

JH Zhang, JD Nolan (joint first authors), SL Kennie, IM Johnston, T Dew, PH Dixon, C Williamson, JRF Walters. Potent stimulation of Fibroblast Growth Factor 19 expression in the human ileum by bile acids. Am J Physiol Gastrointest Liver Physiol. 2013 Mar 21

Nolan, J.D., I.M. Johnston, and J.R.F. Walters, Altered enterohepatic circulation of bile acids in Crohn’s disease and their clinical significance: a new perspective. Expert Review of Gastroenterology & Hepatology, 2012. 7(1): p. 49-56

Nolan JD, I Johnston, JRF Walters. Physiology of malabsorption. Surgery - June 2012; Vol. 30, Issue 6, Pages 268-274

Johnston I, Nolan J, Pattni SS, Walters JRF. New insights into bile acid malabsorption. Curr Gastroenterol Rep 2011; 13:418-25

T.J.S. Cross, A. Quaglia, J. Nolan, S. Hughes and P.M. Harrison. Do steatosis and steatohepatitis impact on sustained virological response (SVR) rates in patients receiving pegylated interferon and ribavirin for chronic hepatitis C infection? Journal of medical virology, Volume 82, Issue 6, May 2010, Pages: 958–964

T. J. S. Cross, V. Calvaruso, M. R. Foxton, P. Manousou, A. Quaglia, F. Grillo, A. P. Dhillon, J. Nolan, T. P. Chang, J. O’Grady, M. A. Heneghan, J. P. O’Beirne, A. K. Burroughs and P. M. Harrison. A simple, noninvasive test for the diagnosis of liver fibrosis in patients with hepatitis C recurrence after liver transplantation. Journal of Viral hepatitis, Volume 17, Issue 9, September 2010, Pages: 640–649

Cheent, K. Nolan, J. Shariq, S. Kiho, L. Pal, A. Arnold, J. Case Report: Fatal case of disseminated BCG infection in an infant born to a mother taking infliximab for Crohn's disease. J Crohns Colitis, 2010. 4(5): p. 603-5

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Private contact details

Telephone Self funding: 01293 778 906, Insured: 01293 778 919
Private secretary Vanessa Thorpe