Fatty cells dysfunction is linked to obesity, according to research

27 September 2011

There is a distinct link between lipid cell dysfunction and diseases such as obesity, diabetes and blood lipid disorders which could require weight loss surgery, a new study suggests.

Researchers at the Karolinska Institutet in Sweden tested 100 patients ranging in weight from slim to massively obese and measured the radioactive isotope carbon-14 in each person.

They looked at how the fat is stored and removed from the fat mass over time in different ages by incorporating the radioactive carbon-14 from atmosphere into the body.

Co-leader of the research Dr Kirsty Spalding said: "We can use measurements of carbon-14 in fat against known levels of 14C in the atmosphere to date-stamp the fat."

The researchers concluded that the fat stored in the fat cells of healthy people is renewed on average six times during the ten years of a fat cell's lifespan but this can be significantly reduced if a person suffers with diseases such as type two diabetes.

According to another study, gastric banding for type two diabetics is a possibility and can have the same results as the surgery on non hyphen diabetics.

Posted by Edward Bartel

Arner, P. et al., "Dynamics of human adipose lipid turnover in health and metabolic disease", Nature, AOP 25 September 2011.

Quick, B.,"Adjustable Gastric Banding and Conventional Therapy for Type 2 Diabetes: A Randomized Controlled Trial" JAMA, 2008.


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