Bone biopsy method highlights link between diabetes and bone fractures

20 January 2016

A team from the University of Southampton has developed a new bone biopsy technique that sheds light on the poorly-understood link between diabetes and osteoporosis.

The study from the university's Medical Research Council Lifecourse Epidemiology Unit has provided insights into why people with type 2 diabetes are at risk of bone fractures, an association that has not previously been explained adequately.

Using their high-resolution peripheral quantitative computed tomography scanning process, it was shown that the cortical component of bone tends to exhibit greater porosity in those with type 2 diabetes compared to those without.

This makes the bones weaker and more susceptible to breakages, an insight that could inform the development of new treatment solutions in future.

Lead researcher Dr Mark Edwards, clinical lecturer at the University of Southampton, said: "This is a very interesting discovery using a very novel technique. We've known for some time that people with type 2 diabetes are at risk of fracture but have not been able to fully explain why."

The study involved a group of 177 men and 155 women, who were around 76 years on average at the time of the study.

Posted by Philip Briggs


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