Early retinal changes in glaucoma identified

12 February 2015

New insight has been found about the early stages of glaucoma, which could help the many people who go blind from the condition.

Glaucoma, which is the second biggest cause of blindness, is usually started from growing pressure on the eye. This elevated force damages and destroys the essential retinal ganglion cells the eye needs to see. 

Now a team at the University of California, San Diego School of Medicine and Shiley Eye Institute have found how some types of retinal ganglion cells are able to change their structures within seven days of elevated eye pressure, while others do not.

Published in the Journal of Neuroscience, their study used a model in the laboratory to examine four subtypes of retinal ganglion cells. The cell types differ by their location in the eye and where they send the majority of their dendrites (cellular branches). 

Within seven days of elevated eye pressure, all retinal ganglion cells that send most or all of their dendrites to the OFF sublamina area of the eye experienced significant rearrangements, such as reductions in number and length of dendritic branches. In contrast, retinal ganglion cells with connections in the ON part of the retina did not.

Posted by Philip Briggs

Health News is provided by Adfero in collaboration with Spire Healthcare. Please note that all copy above is ©Adfero Ltd. and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:

or

Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.

or

Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...

Categories

Ophthalmology

© Spire Healthcare Group plc (2016)