‘Body clock dysregulation underlies obesity’

15 May 2014

Body clock ‘dysregulation’ could be the underlying cause of some obesity-related metabolic disorders, according to new research from a team of Texas A&M University System scientists.

Dr. David Earnest, co-lead author of the study, commented: "Animal sleeping and eating patterns, including those of humans, are subject to a circadian rhythmicity.

"And previous studies have shown an association between the dysregulation of circadian or body clock rhythms and some metabolic disorders."

His colleague, Dr. Chaodong Wu, claims circadian clocks in peripheral tissues and cells power daily rhythms and coordinate many  physiological processes, including inflammation and metabolism.

Dr. Wu added that recent studies suggest disruption of the body clock could play a role in the development of some metabolic diseases, including obesity and diabetes.

The new research demonstrates how eating unhealthy foods cause health problems, but eating them at the wrong time can worsen the issue. It also suggests that time-based treatments could provide better management of metabolic diseases.

Posted by Jeanette Royston

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