Scientists make asthma breakthrough

September 18th 2012

A new study has identified new ways to reduce the risk of asthma attack by impeding the two most significant biological responses that lead to an attack.

In a paper published in the Proceedings of the National Academy of Sciences, researchers demonstrated that a specific calcium-activated chloride channel is significant in reducing two biological processes that contribute to the severity of asthma.

These channels regulate airway secretions and smooth muscle contraction, which are two major factors that could lead to an asthma attack.

Senior author Jason Rock said: "Maybe if we could inhibit both of these processes by blocking this one channel, then we could affect the two symptoms of asthma."

He explained that asthma sufferers exhibit an overabundance of mucus along with hyper-contractility of the smooth muscle, which makes it difficult to move in air and out.

"A lot of people equate that with breathing through a straw," he said.
Posted by Edward Bartel

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