Regenerative medicine ‘improves muscle strength in leg injuries’

1 May 2014

Damaged leg muscles can become stronger and function can be improved through a regenerative approach to medicine, according to the University of Pittsburgh Schools of the Health Sciences.

Senior researcher Stephen F. Badyla explained that when a large amount of muscle is lost the body is unable to respond and replace it sufficiently. Scar tissue is then formed, which drastically reduces strength and function.

Scientists surgically implanted extracellular matrix (ECM) derived from pig bladder, into the injured person’s leg. ECM has been used for many years to repair hernias and treat skin ulcers.

The five participants were unable to walk prior to the procedure as they had lost at least 25 per cent of the muscle in their leg

Three of the men were 20 per cent stronger six months after the surgery. Results for the other patients were not as dramatic, but improved on at least one functional measure.

J. Peter Rubin, lead surgeon, said: "This work represents an important step forward in our ability to repair tissues and improve function with materials derived from natural proteins. There will be more options to help our patients."

Posted by Jeanette Royston


Health News is provided by Adfero in collaboration with Spire Healthcare. Please note that all copy above is ©Adfero Ltd. and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:

or

Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.

or

Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...

Categories

General Surgery

© Spire Healthcare Group plc (2016)