Statin therapy could cut pancreatitis, analysis finds

22 August 2012

Statin therapy has been linked to a reduced risk of pancreatitis in a new analysis that reviewed the cases of more than 150,000 participants.

The study revealed that statin therapy was associated with a cut risk of pancreatitis in patients with normal or mildly elevated triglyceride levels.

Researchers at the University of Glasgow investigated the link between the use of a statin or a fibrate and the incidence of pancreatitis by looking at a number of unpublished large clinical trials.

"Although the present results for both statins and fibrates should be considered hypothesis-generating and the number of pancreatitis cases was small in this trial population at low risk of pancreatitis, the analysis raises questions

regarding the choice of lipid-modifying agents in patients with hypertriglyceridemiam," wrote the authors.

"In those with slightly elevated triglyceride levels, statins appear better supported by the available data than fibrates for preventing pancreatitis."

Authors also noted that lifestyle modifications remain essential when it comes to improving lipid profiles in some individuals.

Posted by Jeanette Royston

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