Overeating 'negatively affects the ability of brain insulin'

18 October 2012

People who choose to overeat on a regular basis could see a malfunction in brain insulin signalling, new research has highlighted.

A study led by Christoph Buettner, associate professor of medicine at the Mount Sinai School of Medicine, also shed light on how this malfunctioning can result in a person become obese or suffering from diabetes.

The researchers underlined in their analysis that this occurs as overeating can impair the brain insulin's ability to suppress the breakdown of fat in adipose tissue.

In order to reach such conclusions, the scientists gave laboratory rats a high-fat diet that was comprised of ten per cent lard for three consecutive days.

This eating strategy not only increased the rats' daily caloric intake by up to 50 per cent, but also affected the brain insulin's ability to suppress glucose release from the liver and lipolysis in fat tissue.

Dr Buettner commented: "When you overeat, your brain becomes unresponsive to these important clues such as insulin, which puts you on the road to diabetes. We believe that what happens in rats also happens in humans."

Posted by Jeanette Royston


Health News is provided by Adfero in collaboration with Spire Healthcare. Please note that all copy above is ©Adfero Ltd. and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:

or

Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.

or

Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...

Categories

Diagnostic imaging

© Spire Healthcare Group plc (2016)