New insights into sudden cardiac arrest revealed

21 January 2015

Bioscience researchers at the University of Kent have published new research detailing the mechanics of hypertrophic cardiomyopathy on a molecular level.

The study focuses on how heart muscles are controlled by calcium in greater depth than previous research. It is hoped that this new level of understanding can lead to treatment of the condition’s underlying causes, rather than waiting for dangerous symptoms to present themselves.

It was discovered that two myosin motors within the muscle are needed to turn on a regulatory unit made up of a further 11 of these motors, which communicate via thin protein filaments. The researchers have also furthered their understanding of precisely how these components interact with each other.

Despite its alarming symptoms, hypertrophic cardiomyopathy affects approximately one in 500 of the population. It recently came to prominence in the media when footballer Fabrice Muamba suffered a cardiac arrest during a match in March 2012.
The study will be published in the Journal of Biological Chemistry on January 23rd.

Posted by ​Phillip Briggs 

 

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