Kidney risk unaffected by statins, research shows

25 June 2013

Taking high-dose statins after surviving a heart attack does not increase the risk of kidney damage, new research has found.

Statins are commonly taken as a means of reducing blood cholesterol levels to reduce the risk of further heart problems, but observational studies have suggested that this could lead to higher risk of kidney damage.

However, a new study has analysed data from two large clinical trials in which patients were randomly assigned either a high or low dose of statins. It found that higher-strength statins did not increase the risk of being hospitalised with kidney problems compared to those who were given lover-strength doses.

Indeed, patients on low and high-strength statin doses had comparable levels of creatinine, a protein which generally reflects overall kidney function.

The preliminary research was presented at American Heart Association’s Emerging Science Series of free webinars.

Lead study author Amy Sarma, M.D., M.H.S., says that the findings “provide important reassurance to clinicians that the use of some high-potency statins will not increase the risk of kidney injury”.

Posted by Edward Bartel

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