Combined exercise and drug therapy shows promise for stroke survivors

16 August 2012

Stroke patients could be helped by a therapy which combines exercise and a neurovascular protective agent, according to a new animal study.

Research published in the journal Restorative Neurology and Neuroscience revealed that a program of exercise and the neuroprotective agent known as S-nitrosoglutathione (GSNO) improved the recovery from stroke.

Lead researcher Avtar K Singh explained: "In our study, GSNO or motor exercise provided neuroprotection, reduced neuronal cell death, maintained tissue structure, and aided functional recovery by stimulating the expression of neuronal repair mediators.

"GSNO in combination with exercise accelerated the rate and enhanced the degree of recovery."

Administration of GSNO was not only found to cut brain injury, but also to improve neurological scores. While exercise alone was not sufficient to reduce the infarct volume, it did improve neurobehavioural functions.

Combining both therapies showed a greater functional improvement than either GSNO or exercise alone.

Posted by Edward Bartel


Health News is provided by Adfero in collaboration with Spire Healthcare. Please note that all copy above is ©Adfero Ltd. and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:

or

Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.

or

Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...

Categories

Cardiac

© Spire Healthcare Group plc (2016)