Intrauterine insemination (IUI) involves a relatively straight-forward laboratory procedure to separate fast-moving sperm from more sluggish or non-moving sperm. The woman will be given a course of drugs to stimulate the production of eggs.

The fast-moving sperm from the partner or donor sample are then placed into the woman's womb using a fine catheter close to the time of ovulation when the egg is released from the ovary.

As the timing of insemination is crucial, the woman's cycle is monitored using ultrasound scans to assess the development of follicles and occasionally urine tests to check for the time of ovulation. The sperm is inseminated when these tests indicate that ovulation is imminent.