Osteoarthritis of the knee
The classical ‘wear and tear’ type of arthritis, progressive loss of articular cartilage in the joint leading to aching pain during and after activities, and loss of movement While not directly inherited, it may have a genetic influence. Repetitive minor injuries from sports which involve twisting and turning such as football and rugby can contribute to the wear over years. Currently this problem is irreversible once it begins, although the symptoms can wax and wane over time with good and bad spells. Overall the problem usually slowly progresses over the years and eventually can lead to significant disability.