Specialist in prostate, bladder and kidney cancerSpecialist treatment with radiotherapy and chemotherapyProstate 'seed' BrachytherapyVMAT IMRT radiotherapyStereotactic Ablative Radiotherapy (SBRT)Access to new drug treatments in clinical trials
Lead clinician for radiotherapy research at the Edinburgh Cancer CentreLead clinician for GU Chemotherapy and Radiation Trials at the Edinburgh Cancer Centre. Collaborative research with Edinburgh University Engineering Department, Royal Dick Veterinary School and Edinburgh Cancer Research Centre to develop a lab on a chip system to measure prostate tumour hypoxia and optimise radiotherapy delivery. Collaborative research with the University of Edinburgh Oncology Physics unit to develop image processing techniques to localise the prostate tumour within the prostate for focal therapy or a radiation dose boost. Toxi-triage co investigator to look at measuring biomarkers of radiation exposure.
Consultant Clinical Oncologist Edinburgh Cancer CentreHonorary Senior Lecturer University of Edinburgh
Fellow of the Royal College of RadiologistsFellow of the Royal College of Physicians of EdinburghBritish Urological GroupSouth East Scotland GU Cancer Group (SCAN)UK and Ireland Brachytherapy Users GroupJournal of the Royal College of Radiologist Editorial Board MemberPreviously a member of the National Cancer Research Network Clinical Trials (NCRN) group for Prostate Cancer and Bladder Cancer
Dr McLaren is a specialist in Genito-Urinary Oncology and runs a large practice offering non-surgical treatment with radiotherapy and chemotherapy for Urological Cancer patients. He has a particular interest in prostate brachytherapy (seeds) and dose escalated hypo-fractionated radiotherapy. Edinburgh was the first Scottish Centre to offer prostate brachytherapy in 2001. State of the art volumetric arc based radiotherapy (VMAT) intensity modulated radiotherapy (IMRT) for prostate cancer is routinely available. In addition the prostate stereotactic ablative radiotherapy (SBRT) service will be up and running by the end of 2015. A business plan is also in place to deliver high dose rate prostate brachytherapy for high-risk prostate cancer and for post radiation, RT salvage. For patients with bladder cancer neo-adjuvant chemotherapy is routinely used before surgery or concurrent chemo-radiotherapy. He is a co-investigator on the UK RAIDER trial investigating dose escalated IMRT for bladder cancer in addition.Chemotherapy and new targeted therapy drugs are an important area of disease management. Dr McLaren has extensive experience in the use of Taxotere chemotherapy Abiraterone, Enzalutamide and Alpharadin for example in prostate cancer and Sunitinib, Pazopanib and Axitinib for renal cancer. He ensures early access to newly licensed effective drugs and entry into clinical trials for new treatments as team leader for Urological cancer trials with in the SE of Scotland. Dr McLaren has a very exciting on-going collaboration with the University of Edinburgh Department of Electrical Engineering, Royal Dick Veterinary School and Edinburgh Cancer Research Centre to develop a micro chip system to provide real time measurements of tumour oxygen levels. In time he hopes to implant this device directly into tumours within the prostate and individualise radiotherapy treatments by timing radiotherapy delivery with peak oxygen levels within the tumour. In addition he is co-investigator on a biomarker of radiation sensitivity project as part of a large European grant and ongoing research with oncology physics to identify tumours more accurately for targeting with radiotherapy via novel imaging processing techniques.
Undergraduate training at St Mary's Hospital Medical School in London from 1983-1989. I also undertook an intercalated BSc in Clinical Science and gained First Class Honours. General Medical training at Queens University Hospital Nottingham. Specialist cancer training at Velindre Cancer Hospital Cardiff. Clinical Fellowship specialising in GU oncology at the British Columbia Cancer Agency, Vancouver. Appointed as Consultant Clinical Oncologist and Honorary Clinical Senior Lecturer at the Edinburgh Cancer Centre in 1998. Dr McLaren is married with two children and a dog and moved back into Edinburgh from East Lothian in 2009. He enjoys playing as much golf and supporting as much rugby as time allows.
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