New gene tied to profound vision loss

19 January 2015

New research has discovered a gene that is tied to an incurable eye disorder - retinitis pigmentosa.

Led by a team at the University of Texas Health Science Center at Houston (UTHealth), the research focused on a large Louisiana family with vision problems. 

The retina reacts much like a film in a camera by converting images into electrical signals that can be processed by the brain. By damaging the retina, retinitis pigmentosa can cause decreased night vision and peripheral vision even in the early stages. Once it starts, the loss of vision is relentlessly progressive and often results in blindness.

Published in the journal Investigative Ophthalmology & Visual Science, Stephen P. Daiger, professor at  UTHealth, and his colleagues found a new gene tied to retinitis pigmentosa. It means there are now more than 60 genes associated with the sight-threatening disease.

The discovery of the new gene - hexokinase 1 (HK1) - is important as it helps affected families cope with the disorder, as well as explaining the biologic basis of these diseases and potential drug treatments for gene therapy.

Posted by ​Phillip Briggs 

 

Health News is provided by Adfero in collaboration with Spire Healthcare. Please note that all copy above is ©Adfero Ltd. and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:

or

Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.

or

Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...

Categories

Ophthalmology

© Spire Healthcare Group plc (2016)