New analysis of old HIV vaccines provides insight

29 August 2014

New analysis of old HIV vaccines has identified something that could potentially protect immune response.

Researchers at Duke Medicine have reanalysed the findings of two historic paediatric HIV vaccine trials with encouraging results. `

The report, published in the Journal of Infectious Diseases, used fresh insights to examine the results from a recent adult HIV vaccine trial where the vaccine was found to reduce the number of infections by around 30 per cent.

This immune response was triggered by antibodies that attached to a specific region of the HIV virus's outer envelope, instead of broadly neutralising antibodies that have been considered vital for widespread vaccine success. However, this more specific antibody response was unknown when the original studies took place.

In the new analysis, the researchers retested the blood samples and found that infant HIV vaccination triggered the new immune response, with some participants still showing this response two years after.

Lead author Genevieve G. Fouda, assistant professor of paediatrics at Duke, said: "...The main goal is to prevent HIV transmission from mother-to-child during the period of breast feeding, inducing a two-year immunity would be long enough to be beneficial."

Posted by Jeanette Royston


Health News is provided by Adfero in collaboration with Spire Healthcare. Please note that all copy above is ©Adfero Ltd. and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:


Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.


Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...



© Spire Healthcare Group plc (2016)