Antibiotics don’t ‘reduce risk of infection in gallbladder surgery patients’

9 July 2014

A lack of antibiotic treatment does not result in a greater risk of infection in patients that have undergone gallbladder removal surgery to treat acute calculous cholecystitis, suggests new research from Amiens University Medical Centre, France.

Acute calculous cholecystitis is the third most common reason for emergency admissions to surgical wards.

Many patients receive postoperative antibiotics to reduce the risk of any subsequent infections, despite there being limited evidence to support the need for such treatment.

To conduct the new study, the research team randomly assigned the treatment to 414 patients with mild or moderate acute calculous cholecystitis. Participants had similar lengths of stay at hospitals and readmission rates.

The results revealed that infection rates were 17 per cent for the non-treatment group and 15 per cent for the participants taking antibiotics, which led the scientists to conclude the lack of treatment was not associated with worse outcomes.

Dr Jean Marc Regimbeau, lead author of the study, commented: "It is well known that continuation of antibiotic treatment increases costs and promotes the selection of multiresistant bacteria.”

He added the reduction of antibiotic treatments is needed as their resistance to such drugs is becoming more prevalent.

Posted by Edward Bartel

Health News is provided by Adfero in collaboration with Spire Healthcare. Please note that all copy above is ©Adfero Ltd. and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:


Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.


Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...



© Spire Healthcare Group plc (2016)