Antibiotics don’t ‘reduce risk of infection in gallbladder surgery patients’

9 July 2014

A lack of antibiotic treatment does not result in a greater risk of infection in patients that have undergone gallbladder removal surgery to treat acute calculous cholecystitis, suggests new research from Amiens University Medical Centre, France.

Acute calculous cholecystitis is the third most common reason for emergency admissions to surgical wards.

Many patients receive postoperative antibiotics to reduce the risk of any subsequent infections, despite there being limited evidence to support the need for such treatment.

To conduct the new study, the research team randomly assigned the treatment to 414 patients with mild or moderate acute calculous cholecystitis. Participants had similar lengths of stay at hospitals and readmission rates.

The results revealed that infection rates were 17 per cent for the non-treatment group and 15 per cent for the participants taking antibiotics, which led the scientists to conclude the lack of treatment was not associated with worse outcomes.

Dr Jean Marc Regimbeau, lead author of the study, commented: "It is well known that continuation of antibiotic treatment increases costs and promotes the selection of multiresistant bacteria.”

He added the reduction of antibiotic treatments is needed as their resistance to such drugs is becoming more prevalent.

Posted by Edward Bartel


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