Researchers reveal new mechanism for pain management

4 September 2014

A team at the University of Calgary's Hotchkiss Brain Institute have found a new mechanism that can reverse chronic pain. Led by neuroscientist Dr Gerald Zamponi, the group created an animal model and found that pain signals could be shut off in nerve cells by interfering with a specific enzyme.

Published in the journal Neuron, the findings call for further research, which Dr Zamponi is now trying to secure from the Centre for Drug Research and Development in Vancouver. These studies would attempt to develop a drug that could improve the lives of those suffering with chronic conditions such as arthritis, irritable bowel disease and neuropathic pain. 

Dr Zamponi, the lead author of the study, said that chronic pain can be debilitating for many people but is only controlled by the poor available treatments.

"Our discovery opens the door towards new treatments, and based on the data that we have so far, it is a viable strategy," he added.

Posted by Jeanette Royston


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