Strokes linked to adverse outcomes after surgery

16 July 2014

A study that analysed more than 480,000 patients who underwent elective noncardiac surgery, found that a history of strokes was associated with an increased risk of major adverse cardiovascular events and death.

The research, published in the Journal of the American Medical Association (JAMA), discovered that this was particularly evident if there was less than nine months between the stroke and surgery.

Mads E Jørgensen, MB, of the University of Copenhagen, and colleagues investigated the association between prior stroke and the risk of major adverse cardiovascular events (MACE, including ischemic stroke, heart attack, and cardiovascular death) and death up to 30 days after surgery.

Previously, non-cardiac surgeries performed on patients with a recent heart attack or stent implantation have been linked to an increased risk of perioperative cardiac events and bleeding compared to patients with more distant heart attack or stent placement. However, there has been little research done to determine whether or not the timing of surgery in patients with prior strokes could increase their risk.

"Our findings need to be confirmed but may warrant consideration in future perioperative guidelines," the authors concluded.

Posted by Edward Bartel


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