New study indicates future feasibility of ovarian transplants

3 November 2016

Ovarian transplants may become possible in future, according to an international team of researchers.

Led by MedUni Vienna, the scientists have been able to successfully transplant an ovary from one baboon to another, even managing to restore a functional monthly cycle in one of the individuals.

This was achieved with new immunosuppressive agent known as preimplantation factor (PIF), which was administered both before and after transplantation and was shown to work well, without serious side effects.

Study leader Michael Feichtinger from MedUni Vienna's department of obstetrics and gynaecology said: "These results would suggest that successful ovarian transplantation might be possible in future."

Currently, around 11 per cent of women worldwide suffer from premature ovarian failure from various different causes, including as a side effect of chemotherapy. This can cause even very young women to prematurely enter menopause.

Not only does this stop them from getting pregnant, but the associated drop in hormone levels can also prematurely trigger osteoporosis and other menopausal complications.

Posted by Philip Briggs

 


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