New nanoparticle therapy offers means of targeted liver cancer treatment

9 February 2016

US scientists have developed an experimental nanoparticle therapy with the potential to aid the treatment of liver cancer.

Created by the University of Texas Southwestern Medical Center, the method involves using a combination of low-density lipoproteins (LDL), a cholesterol carrier, and omega-3 fish oil as a means of selectively combating liver cancer cells.

The presence of the cholesterol-carrying proteins means the liver cancer cells will absorb the nanoparticles, with the aim of acquiring nutritional building blocks to help the tumour grow and proliferate.

However, fish oil is selectively toxic to cancer cells, meaning the LDL acts as a Trojan horse to convey the omega-3, which can help kill off the tumour while leaving the healthy cells unharmed.

An experiment involving lab rats showed that 80 per cent of the subjects' tumour cells were dying after three days of treatment with the nanoparticle.

Dr Ian Corbin, senior author of the study and an assistant professor at the University of Texas Southwestern Medical Center, said: "This approach offers a potentially new and safe way of treating liver cancer, and possibly other cancers."

Posted by Jeanette Royston

 


Health News is provided by Axonn Media in collaboration with Spire Healthcare. Please note that all copy above is ©Axonn Media and does not reflect views or opinions of Spire Healthcare unless explicitly stated. Additional comments on the page from individual Spire consultants do not necessarily reflect the views or opinions of other consultants or Spire Healthcare.

Find a treatment, test or scan available at:

or

Find a consultant

Use one or more of the options below to search for a consultant and link through to view their Spire profile.

or

Let us help you

fill out this form and we will get back to you:

Please select a hospital

We can call you

Please enter your details below and we will call you back.

What is the aim of your enquiry?

Please select a hospital

If we are unable to reach you by phone, please include your email address so that we can get in touch...

Categories

Cancer

© Spire Healthcare Group plc (2016)