New genetic variants linked to brain cancer

1 October 2015

A total of five new genetic variants have been linked to glioma, which is the most common form of brain cancer.

Researchers at the Institute of Cancer Research compared the genetic profiles of 5,637 people who had developed glioma with 9,158 people without the disease. The findings bring the number of genetic variations linked to the disease to 12.

Notably, one variant was found to increase the risk of suffering from glioblastoma by 23 per cent. This is a particularly severe type of brain cancer with an average survival time of ten to 15 months. The other four variants have been associated with less lethal forms of glioma, with each increasing the risk by approximately five per cent.

Lead researcher Richard Houlston said: "We believe our study is the largest ever conducted of the genetics of glioma - the most common form of brain cancer - and it provides firm evidence that susceptibility to the disease is in part inherited.”

Posted by Jeanette Royston


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