Sunday 12th December - Radiotherapy
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Will I need radiotherapy after surgery for breast cancer and how effective is it?
Jennifer, Broxburn |
Professor Ian Kunkler is a Radiation Oncologist at Spire Edinburgh Hospitals.
About 70% of patients with early breast cancer having a sufficiently small a lump for it to be locally excised rather than require a mastectomy. This is normally followed by a course of radiotherapy over a few weeks as an outpatient.Beams of Xrays directed at the breast aims to sterilise any residual cancer cells in the breast.
Mature studies show that radiotherapy is a highly effective treatment, reducing the risk of breast cancer returning in the breast within 5 years by a factor of 4 or 5. An important additional benefit is that radiotherapy also the risks of death from breast cancer.
Some patients with larger breast cancers or where is there is evidence of cancer at several different sites in the breast will require removal of the breast (mastectomy). Not all patients will require radiotherapy after this form of surgery. Only patients at higher risk of recurrence are advised to undergo radiotherapy. For such patients radiotherapy reduces the risk of recurrence at the site of original surgery by 60% and confers an additional 9-10% survival benefit. For patients are lower risk of recurrence, the need for radiotherapy is being studied in an international trial based in Edinburgh. In future it may be possible to identify a molecular ‘signature’ on the cells of a patient’s breast cancer. This may help in the selection of patients most likely to benefit of radiotherapy.